Original classroom practice · grades 6–12
Biology vocabulary crossword vocabulary pack
Practice core terms from cells, genetics, biomolecules, energy processes, inheritance, and adaptation.
Teacher move: Have students connect each answer to a labeled cell, inheritance example, or biological process.
| # | Clue | Letters | Level | Candidate and evidence |
|---|---|---|---|---|
| 1 | Body-cell division that produces matching nuclei | 7 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 2 | Cell division that halves chromosome number for gametes | 7 | advanced | Candidate: ____________________ Evidence: __________________________________ |
| 3 | Threadlike DNA package in a cell nucleus | 10 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 4 | DNA segment linked to a trait | 4 | introductory | Candidate: ____________________ Evidence: __________________________________ |
| 5 | Version of a hereditary DNA unit | 6 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 6 | An organism's allele combination | 8 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 7 | Observable expression of a trait | 9 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 8 | Cell structure where proteins are assembled | 8 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 9 | Plant organelle that captures light to make sugar | 11 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 10 | Organelle where much cellular ATP is produced | 13 | advanced | Candidate: ____________________ Evidence: __________________________________ |
| 11 | Membrane-bound cell compartment holding DNA | 7 | introductory | Candidate: ____________________ Evidence: __________________________________ |
| 12 | Movement from higher concentration to lower concentration | 9 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 13 | Movement of materials across a cell membrane | 9 | introductory | Candidate: ____________________ Evidence: __________________________________ |
| 14 | Biological molecule that speeds a reaction | 6 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 15 | Macromolecule made from amino acids | 7 | introductory | Candidate: ____________________ Evidence: __________________________________ |
| 16 | Fat-like biomolecule that does not mix well with water | 5 | introductory | Candidate: ____________________ Evidence: __________________________________ |
| 17 | Biomolecule group that includes sugars and starches | 12 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 18 | Cell process that releases energy from food molecules | 11 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 19 | Energy process cells can use without oxygen | 12 | intermediate | Candidate: ____________________ Evidence: __________________________________ |
| 20 | Inherited trait that helps survival or reproduction | 10 | introductory | Candidate: ____________________ Evidence: __________________________________ |
Reflection
Which clue detail gave you the strongest evidence, and what did it rule out?
Teacher key
- MITOSIS · 7 letters · noun · intermediate
Body-cell division that produces matching nucleiHint: This process supports growth and tissue repair.
Why it fits: MITOSIS fits because ordinary body cells use this process to make cells with the same chromosome set. - MEIOSIS · 7 letters · noun · advanced
Cell division that halves chromosome number for gametesHint: It helps offspring differ from their parents.
Why it fits: MEIOSIS is correct because sperm and egg cells form through divisions that reduce and shuffle chromosomes. - CHROMOSOME · 10 letters · noun · intermediate
Threadlike DNA package in a cell nucleusHint: Humans usually have 46 of these in body cells.
Why it fits: CHROMOSOME fits because it is the organized structure that carries hereditary information inside many cells. - GENE · 4 letters · noun · introductory
DNA segment linked to a traitHint: A short hereditary unit can influence a characteristic.
Why it fits: GENE is correct because traits are influenced by DNA segments passed from parents to offspring. - ALLELE · 6 letters · noun · intermediate
Version of a hereditary DNA unitHint: For a blood type trait, A and O are examples.
Why it fits: ALLELE fits because organisms can carry different versions of a gene that affect how a trait appears. - GENOTYPE · 8 letters · noun · intermediate
An organism's allele combinationHint: Letters like Bb can represent it in a Punnett square.
Why it fits: GENOTYPE is correct because it names the genetic makeup represented by allele symbols, not the visible trait itself. - PHENOTYPE · 9 letters · noun · intermediate
Observable expression of a traitHint: Flower color or pea shape can be this visible result.
Why it fits: PHENOTYPE fits because it names the visible or measurable form of a trait, such as height or color. - RIBOSOME · 8 letters · noun · intermediate
Cell structure where proteins are assembledHint: It reads RNA instructions during translation.
Why it fits: RIBOSOME is correct because this cellular machine translates RNA messages into chains of amino acids. - CHLOROPLAST · 11 letters · noun · intermediate
Plant organelle that captures light to make sugarHint: It contains green pigment and is common in leaf cells.
Why it fits: CHLOROPLAST fits because this organelle houses the reactions that convert light energy into chemical energy. - MITOCHONDRION · 13 letters · noun · advanced
Organelle where much cellular ATP is producedHint: It is often nicknamed the cell's power site.
Why it fits: MITOCHONDRION is correct because many eukaryotic cells rely on this organelle for large amounts of usable energy. - NUCLEUS · 7 letters · noun · introductory
Membrane-bound cell compartment holding DNAHint: In many diagrams, it is drawn as the large central cell part.
Why it fits: NUCLEUS fits because it houses chromosomes and helps regulate cell activities through genetic instructions. - DIFFUSION · 9 letters · noun · intermediate
Movement from higher concentration to lower concentrationHint: A drop of dye spreading through water shows the idea.
Why it fits: DIFFUSION is correct because particles tend to spread out until their concentration becomes more even. - TRANSPORT · 9 letters · noun · introductory
Movement of materials across a cell membraneHint: It may require energy when particles move against a gradient.
Why it fits: TRANSPORT fits because cells use passive and energy-requiring mechanisms to move substances where they are needed. - ENZYME · 6 letters · noun · intermediate
Biological molecule that speeds a reactionHint: It lowers activation energy and is not used up.
Why it fits: ENZYME is correct because cells rely on these catalysts to make many reactions occur fast enough for life. - PROTEIN · 7 letters · noun · introductory
Macromolecule made from amino acidsHint: Enzymes and many cell structures are built from this material.
Why it fits: PROTEIN fits because chains of amino acids form molecules that support structure, signaling, transport, and catalysis. - LIPID · 5 letters · noun · introductory
Fat-like biomolecule that does not mix well with waterHint: Cell membranes contain a double layer of this molecule type.
Why it fits: LIPID is correct because these molecules store energy, form membranes, and resist mixing with water. - CARBOHYDRATE · 12 letters · noun · intermediate
Biomolecule group that includes sugars and starchesHint: Cells often use this molecule type for quick energy or structure.
Why it fits: CARBOHYDRATE fits because glucose, starch, and cellulose all belong to this energy and structure-related molecule group. - RESPIRATION · 11 letters · noun · intermediate
Cell process that releases energy from food moleculesHint: Its aerobic form uses oxygen and produces ATP.
Why it fits: RESPIRATION is correct because cells convert chemical energy in molecules such as glucose into ATP through this process. - FERMENTATION · 12 letters · noun · intermediate
Energy process cells can use without oxygenHint: Yeast use it when making bread rise.
Why it fits: FERMENTATION fits because it regenerates molecules needed for glycolysis when oxygen is unavailable. - ADAPTATION · 10 letters · noun · introductory
Inherited trait that helps survival or reproductionHint: Thick fur in a cold habitat can be one example.
Why it fits: ADAPTATION is correct because natural selection can favor traits that help organisms succeed in particular conditions.
Accept a different answer only when it matches the clue, length, grammar, and any supplied crossings. Use the reviewed answer when teaching the intended vocabulary target.
All clues in this pack are original classroom material from Crossword Clue Tutor and may be printed for classroom use.